Ozone Treatment of Alveolar Bone in the Cape Chacma Baboon Does Not Enhance Healing Following Trauma
Identifieur interne : 002327 ( Main/Exploration ); précédent : 002326; suivant : 002328Ozone Treatment of Alveolar Bone in the Cape Chacma Baboon Does Not Enhance Healing Following Trauma
Auteurs : Marthinus Kotze [Afrique du Sud] ; Kürt-W Bütow [Afrique du Sud] ; Steve A. Olorunju [Afrique du Sud] ; Harry F. Kotze [Afrique du Sud]Source :
- Journal of Maxillofacial & Oral Surgery [ 0972-8279 ] ; 2013.
Abstract
In the international literature, the role of Ozone (O3) in the advancement in alveolar bone healing in the absence of bone pathology was not tested before. The purpose of this study was to evaluate alveolar bone regeneration after a bone defect was created and treated with a single topical administration of O3. Alveolar bone defects were created on five healthy chacma baboons. One side of the maxilla and mandible was topically treated with a single treatment of an O3/O2 mixture (3,5–4 % O3), while the opposite sides were not treated and thus served as control. Regeneration was measured radiologically, using a standardized gray scale, as the increase in bone density in the treatment area at 3 and 6 weeks post-operative and was statistically analyzed using multivariate analysis of variance (MANOVA). There were no significant differences in densities observed between the O3/O2 mixture treatment and the control (
Url:
DOI: 10.1007/s12663-013-0471-1
PubMed: 24822005
PubMed Central: 4016407
Affiliations:
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Olorunju</name><affiliation wicri:level="1"><nlm:aff id="Aff3">Medical Research Council, Pretoria, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Medical Research Council, Pretoria</wicri:regionArea><wicri:noRegion>Pretoria</wicri:noRegion></affiliation></author><author><name sortKey="Kotze, Harry F" sort="Kotze, Harry F" uniqKey="Kotze H" first="Harry F." last="Kotze">Harry F. Kotze</name><affiliation wicri:level="1"><nlm:aff id="Aff4">Faculty of Health Sciences, University of The Free State, Bloemfontein, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Faculty of Health Sciences, University of The Free State, Bloemfontein</wicri:regionArea><wicri:noRegion>Bloemfontein</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Maxillofacial & Oral Surgery</title><idno type="ISSN">0972-8279</idno><idno type="eISSN">0974-942X</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In the international literature, the role of Ozone (O<sub>3</sub>) in the advancement in alveolar bone healing in the absence of bone pathology was not tested before. The purpose of this study was to evaluate alveolar bone regeneration after a bone defect was created and treated with a single topical administration of O<sub>3</sub>. Alveolar bone defects were created on five healthy chacma baboons. One side of the maxilla and mandible was topically treated with a single treatment of an O<sub>3</sub>/O<sub>2</sub> mixture (3,5–4 % O<sub>3</sub>), while the opposite sides were not treated and thus served as control. Regeneration was measured radiologically, using a standardized gray scale, as the increase in bone density in the treatment area at 3 and 6 weeks post-operative and was statistically analyzed using multivariate analysis of variance (MANOVA). There were no significant differences in densities observed between the O<sub>3</sub>/O<sub>2</sub> mixture treatment and the control (<italic>p</italic> > 0.05). A single O<sub>3</sub> treatment did not increase alveolar bone healing over a 3- and 6-week period in the mandible and the maxilla.</p></div></front></TEI><affiliations><list><country><li>Afrique du Sud</li></country></list><tree><country name="Afrique du Sud"><noRegion><name sortKey="Kotze, Marthinus" sort="Kotze, Marthinus" uniqKey="Kotze M" first="Marthinus" last="Kotze">Marthinus Kotze</name></noRegion><name sortKey="Butow, Kurt W" sort="Butow, Kurt W" uniqKey="Butow K" first="Kürt-W" last="Bütow">Kürt-W Bütow</name><name sortKey="Kotze, Harry F" sort="Kotze, Harry F" uniqKey="Kotze H" first="Harry F." last="Kotze">Harry F. Kotze</name><name sortKey="Olorunju, Steve A" sort="Olorunju, Steve A" uniqKey="Olorunju S" first="Steve A." last="Olorunju">Steve A. Olorunju</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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